I am having similar issues. My setup was working fine until one of the enclosures died. I bought the same enclosure, 5-bay mobius. My setup consists of the following: eSata connection, 2 5-bay drives, and JBOD setup. The new 5-bay enclosure keeps dropping 4 of the 5 drives from the system. They all come back after a reboot and then drops during the rebuild of the pool. All of the drives are a year or less old. I ran Scandisk on a separate computer and the drives are functioning fine. I also changed out the eSata cable. Any help will be greatly appreciated.