Yes I am running 2 Mobius 5 Bay Enclosures connected to the Tempo Sata Pro 6Gb 4-port, port multiplier. It worked great on my old Windows Server 2016 but I recall I had to jump through some hoops to get it working but I can't remember the steps. It is not working at all on my Windows Server 2022. It is very frustrating because my Server 2016 backup is corrupted, so I am all in on Server 2022.