Thanks for the awesome replies fellas!
@otispresley - That is an impressive setup indeed! I think it may be overkill for my needs, but it's great to see the variations that can be achieved for such setups.
@drashna - I appreciate the extra info about recovering the DrivePool, as hardware is one thing, but being able to access my existing data once I've built the server is obviously important. I think I am going to go with the Norco 4220 case, but with regards to the controller, I'm leaning towards the LSI card, however I'm not sure if I should get two, or just the one and then use an S