Hi, im just posting here because I think i might be experiencing a similar issue. I am on Win 7 64bit, when the scanner service is running i am experiencing intermittent 'lock ups' lasting about a third of a second. The mouse stops moving and any audio turns into buzzing.
I am using the 4 port Sata Pci express card with Marvell Chipset, same one?:
Edit, Sorry very slightly different model from posted link, 2 eSata ports not one: http://www.amazon.co.uk/StarTech-com-eSATA-Express-Controller-Adapter/dp/B0010VDI0M
It has 4 drives plugged in. I am also experiencing problems with the card not returning correct HDD serial numbers, i get either '?', a jumbled serial no. (which is still interpretable or something that looks like its encoded like 45620202002002 etc). I appreciate this is probably an issue with the card rather than the scanner itself.
Is the locking up probably the card? Id like to avoid changing it since it was expensive and resolved problems I was having with other sata extension cards.